Oz Biosciences Spike SARS-Cov-2 Antigen mRNA Modified

OVA mRNAs have been designed to produce high expression level of Ovalbumin protein. Spike SARS CoV-2 DELTA mRNAs have been designed to produce high expression level of DELTA mutant spike protein of SARS-CoV-2 virus. Spike SARS CoV-2 (E484K; N501Y) mRNAs have been designed to produce high expression level of spike protein of SARS-CoV-2 virus.

OZB mRNAs are produced by in vitro transcription. mRNAs are stabilised at the 5’ end by modified nucleotides capping (Cap1) and contain a poly(A) tail at the 3’ end. Sequences have been optimised to yield improved stability and performance. Available as unmodified or modified versions: modified with 5-methoxyuridine (5moU replaces U) to reduce innate immune responses or modified with N1-methyl-pseudouridine (N1-mψ) to reduce innate immune response.