Analysis Note

Evaporation Number: 1.9

Application

Methanol is a high-purity solvent used as a mobile phase component in ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS) analysis.The product is used as a solvent in studies such as the following:high resolution mass spectrometric (HRMS) analysis of per- and polyfluoroalkyl substances (PFAS) in environmental water samplesUHPLC-MS/MS study of PFAS and/or perfluorooctane sulfonate (PFOS) in sewage sludge and soil samples

Features and Benefits

suitability tested and specified for UHPLC-MS and UHPLC-UV: for analytical flexibility specified quality in positive and negative in positive and negative electrospray ionization (ESI) and atmospheric-pressure chemical ionization-mass spectrometry (APCI-MS) for lowest detection limits and confidence in analyses for all important MS modes (test 1)R12;ESI/APCI (+) ﹤ 2 ppbR12;ESI/APCI (-) ﹤ 10 ppb lowest impurity profile: for interference-free baselines (test 2) microfiltered through 0.2 µm filter (test 3) to provide:R12;a long lifespan to filters and mechanical parts of HPLC systemsR12;reduced risk of column clogging packed in borosilicate glass bottles for minimized metal ion contaminations lowest levels of trace metal impurities for a minimum metal ion adduct formationR12; ﹤5 ppb lowest level of polyethylene glycol (PEG) impurities in UHPLC-MS solvent lineup (PEG S/N signal-to-noise-ratio ﹤ 50)

General description

UHPLC-MS LiChrosolv^® solvents are designed to meet the highest requirements of UHPLC-MS in research and quality control, including proteomics and metabolomics and environmental, clinical, food or industrial testing applications

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany