Non disponible en dehors du Royaume-Uni et de l'Irlande

Amino Acid Sequence

Arg-Pro-Arg-Ala-Ala-Thr-Phe-NH2

Application

AKT refers to the serine/threonine protein kinases, AKT-1, AKT-2 and AKT-3, which are involved in the cellular processes of glucose metabolism, cell proliferation, apoptosis, transcription and cell migration. The peptide Arg-Pro-Arg-Ala-Ala-Thr-Phe may be a relatively specific substrate for PKBA (AKT-1) because, unlike other substrates, it is not phosphorylated by p70 S6 kinase or MAP kinase activated protein (MAPKAP) kinase-1.