Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

This recombinant variant is recommended for use in absorption, distribution, metabolism, and excretion (ADME) pharmacological research; cell culture; drug delivery research; and cryopreservation of cells.

Biochem/physiol Actions

Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood.

Legal Information

Albagen is a trademark of Albumin Therapeutics, LLC.

Other Notes

View more information on human serum albumin.

Physical form

Solution in phosphate buffered saline containing 4 mM sodium caprylate and 4 mM N-acetyltryptophan.

Physical properties

Recombinant construct with N-terminal deletion of Asp. Structurally equivalent to native albumin by x-ray crystallography. The N-terminal Asp is the principal Cu²⁺ and Ni²⁺ chelation site; its deletion eliminates an important antigenic determinant, and the protein is hypoallergenic. Also blocked at Cys³⁴ to improve stability, monomer content and homogeneity.