Fragment de bêta-protéine acétyl-amyloïde 15-20 μ, >=97% (HPLC), poudre

Code: a6933-1mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Amino Acid Sequence

Ac-Gln-Lys-Leu-Val-Phe-Phe-NH2

Biochem/physiol Actions

Amyloid plaques characteristic of the Alzheimer brain contain fibrils ...


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$97.01 1MG
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Non disponible en dehors du Royaume-Uni et de l'Irlande

Amino Acid Sequence

Ac-Gln-Lys-Leu-Val-Phe-Phe-NH2

Biochem/physiol Actions

Amyloid plaques characteristic of the Alzheimer brain contain fibrils composed of amyloid beta aggregates. Short peptides containing the sequence KLVFF have been shown to bind specifically to the homologous region in Aβ and are used to prevent full length amyloid fibril formation.

Packaging

1 mg in glass bottle

assay≥97% (HPLC)
colorwhite
formpowder
Gene Informationhuman ... APP(351)
InChI keyDDXTVYDSGCHGAN-PITCCTKHSA-N
InChI1S/C42H63N9O8/c1-25(2)22-33(49-38(55)30(18-12-13-21-43)47-39(56)31(46-27(5)52)19-20-35(44)53)41(58)51-36(26(3)4)42(59)50-34(24-29-16-10-7-11-17-29)40(57)48-32(37(45)54)23-28-14-8-6-9-15-28/h6-11,14-17,25-26,30-34,36H,12-13,18-24,43H2,1-5H3,(H2,44,53)(H2,45,54)(H,46,52)(H,47,56)(H,48,57)(H,49,55)(H,50,59)(H,51,58)/t30-,31-,32-,33-,34-,36-/m0/s1
Quality Level200
SMILES stringCC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(C)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc2ccccc2)C(N)=O
storage temp.−20°C
UniProt accession no.P05067
Cas Number189064-06-0
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