Non disponible en dehors du Royaume-Uni et de l'Irlande

Amino Acid Sequence

Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 [Disulfide Bridge: 1-6]

Application

[Arg8]-Vasopressin acetate salt has been:used as a vasopressin receptor agonist to test vasopressin receptorsused to evoke peripheral V1a receptor-mediated vasoconstrictionas a supplement in Ham′s F12/Dulbecco′s modified Eagle′s medium for proximal tubule and glomerular explant cell culture

Biochem/physiol Actions

Endogenous antidiuretic hormone in most mammalian species. It is released into the blood from nerve terminals in the posterior pituitary and median eminence. Arg⁸-vasopressin is also a neurotransmitter in the central nervous system. It is implicated in a variety of physiological processes including diuresis, vasoregulation, and memory. Regulates water balance by antidiuretic action; contracts arterioles (vasopressor action).

General description

Arginine vasopressin is a nonapeptide. It is produced by anterior hypothalamus nerve cells.

Other Notes

Lyophilized from 0.5% acetic acid

Preparation Note

[Arg8]-Vasopressin acetate salt dissolves water at 20 mg/ml to yield a clear colorless to faint yellow solution.