Non disponible en dehors du Royaume-Uni et de l'Irlande
General description
Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. PARG hydrolyzes poly(ADP-ribose) at glycosidic (1′′-2′) linkage of ribose-ribose bond to produce free ADP-ribose.
Other Notes
Human PARG is fused to a His-tag.
Physical form
Solution in 50 mM TRIS-HCl, pH 7.5, containing 100 mM sodium chloride, 0.2% NP-40, 50 mM imidazole and 10% glycerol.
Ce produit répond aux critères suivants: