Non disponible en dehors du Royaume-Uni et de l'Irlande

General description

TESK1 or testis-specific kinase 1 is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain which is most closely related to those of the LIM motif-containing protein kinases (LIMKs). TESK1 protein can phosphorylate myelin basic protein and histone in vitro and plays an important role at and after the meiotic phase of spermatogenesis. TESK1 is mainly expressed in testicular germ cells.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Preparation Note

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.