Non disponible en dehors du Royaume-Uni et de l'Irlande

General description

OSR1 is a member of the Ser/Thr family of protein kinases. OSR1 is activated by osmotic stresses and regulates the downstream protein kinase such as PAK1 in order to establish the sensor/signaling modules that initiate the cellular response to environmental stress. OSR1 can be phosphorylated by ATM or ATR during DNA damage process.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Preparation Note

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.