Application
Saponin from Quillaja bark has been used:to stain CD4+ and CD8+ T-cellsto lyse trophozoite-infected red blood cellsin immunohistochemical staining
Biochem/physiol Actions
Potent hemolytic when injected i.v.; surfactant that enhances penetration of proteins and other macromolecules through cell membranes; it also has been used as an adjuvant for vaccines.
Saponins solubilize the low density lipoprotein (LDL) fraction of cholesterol in micelles, thus lowering their concentration. Saponin from Quillaja bark is used as a flavoring agent in food and beverages. This saponin has been shown to enhance immune-cell proliferation in vitro.
Saponins are associated with many biological and pharmacological activities. It is known to stimulate immune response in mammals. Hence it is used as vaccine adjuvants. Saponins possesses antiviral, antifungal, antitumor, anti-inflammatory, hypoglycemic and hypocholesterolemic effects.
General description
Saponins are natural steroidal glycoside (terpenes).
Packaging
25, 100 g in poly bottle
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