RSK4, actif, humain étiqueté GST, PRECISIO Kinase, recombinant, exprimé en cellules bactériulovirus infectées Sf9 ,>=70% (SDS-PAGE), solution aqueuse tamponnée de glycérol

Code: r8157-10ug D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

RSK4 is a member of the 90-kDa ribosomal S6 kinase family which are important components of growth factor mediated stimulation of cellular proliferati...


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£455.00 10UG

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

RSK4 is a member of the 90-kDa ribosomal S6 kinase family which are important components of growth factor mediated stimulation of cellular proliferation, survival and differentiation. RSK4 is activated via coordinated phosphorylation by ERK and 3-phosphoinositide-dependent protein kinase-1 (PDK1). RSK4 is often associated with contiguous gene syndromes consisting of X-linked deafness type 3 (DFN3), mental retardation (MRX) and choroideremia (CHM). RSK4 is most abundantly expressed in the brain and kidney.

Legal Information

PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

assay≥70% (SDS-PAGE)
formbuffered aqueous glycerol solution
Gene Informationhuman ... RPS6KA6(27330)
mol wt~112 kDa
product linePRECISIO® Kinase
Quality Level200
recombinantexpressed in baculovirus infected Sf9 cells
shipped indry ice
specific activity459-621 nmol/min·mg
storage temp.−70°C
UniProt accession no.Q9UK32
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