Non disponible en dehors du Royaume-Uni et de l'Irlande
Amino Acid Sequence
Ac-Nle-cyclo(Asp-His-Nal-Arg-Trp-Lys-NH2)
Biochem/physiol Actions
Screening analogs of the cyclic lactam melanocortin agonist MTII led to the identification of the agoutimimetic SHU9119. This compound shares pharmacological properties with the agouti peptide in that it is a potent antagonist of the melanocortin-4 receptor and a less potent antagonist of the melanocortin-3 receptor.
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