Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

HIPK4 (homeodomain-interacting protein kinase 4) is serine/threonine kinase protein. HIPK4-mediated phosphorylation of p53 is crucial for p53-associated transcriptional repression.

General description

HIPK4 (homeodomain-interacting protein kinase 4) is present in the lungs and white adipose tissues. The protein mainly localizes in the cytoplasm. However, a weak signal is also present in the nucleus.

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Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.