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Analysis Note
The biological activity is measured by its ability to stimulate the proliferation of human AML5 cells.
Biochem/physiol Actions
Flt-3/Flk-2 Ligand (FL, or Flt-3L) is a transmembrane glycoprotein that binds and activates the Flt-3 receptor. Expression of Flt-3 is primarily restricted among hematopoietic cells to the most primitive progenitor cells.
General description
Mouse and human Flt-3 ligand share ~72% homology and both demonstrate cross-species activity.
Physical form
Lyophilized, 0.2 µm sterile filtered, with with 0.5x PBS.
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