Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Factor V is a key component in blood coagulation systems, where deficiencies can inhibit thrombin generation and affect hemostasis. It has been used in studies of Coagulopathic bleeding which occurs following injury and is a leading cause of in hospital deaths.

General description

Factor V is a single chain glycoprotein involved in the blood coagulation cascade. It is the procofactor of Va which accelerates the conversion of prothrombin to thrombin.

Linkage

View this factors role in the Coagulation Cascade.

Physical form

Aqueous solution containing 50% (v/v) glycerol

Unit Definition

One unit is equivalent to the Factor V activity in 1.0 mL of normal human plasma at pH 7.4 at 37 °C.