Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

The BMX gene encodes a novel non-receptor tyrosine kinase, which may play a role in the growth and differentiation of hematopoietic cells. Bmx induces the activation of the Stat-signaling pathway.

Physical form

Solution of 50 µL in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, and 30% glycerol.

Unit Definition

Kinase activity is measured as the molar amount of phosphate incorporated into Poly Glu-Tyr substrate per minute per mg protein at 30 °C using a final concentration of 50 µM [³²P]-ATP.