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Amino Acid Sequence

Arg-Gly-Asp

Application

Arg-Gly-Asp has been used:to saturate the cell surface Arg-Gly-Asp (RGD) receptors and inhibit marrow stromal cell (MSC) attachment to peptide modified hydrogelin adhesion assayin inhibition assay to confirm the β1-integrin-dependency of cell adhesionin textile fabrication and RGD textile functionalizationto engineer a population of human dermal fibroblasts with impaired migrationto modify glass substrate and evaluate the behavior of human bone marrow mesenchymal stem cells (hBM-MSCs)in the cell culture of human mammary epithelial cells

Biochem/physiol Actions

Primary sequence involved with the binding of proteins to cell surfaces

General description

Arg-Gly-Asp (RGD) is an integrin binding site, which belongs to the class of adhesive proteins. It functions as a brain tumor targeting ligand.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. A8052.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Preparation Note

Tripeptide from the cell-attachment domain of fibronectin