Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

8.8 MAG may be used as a host lipid to grow MdfA (multidrug transporter protein)–YN1074 (Fab fragment) complex grown using the lipidic cubic phase (LCP) crystallization method.

Biochem/physiol Actions

Monoacylglycerols are used in lotions, ointments and deodorants. It serves as a lubricant, antistatic and plastifying agent, hence it is very useful in the plastic industry.

General description

Monoacylglycerols (MAGs) are glycerol esters, that can be produced by the glycerolysis of triglycerides and alkyl esters. MAGs are polar lipids and amphiphilic in nature.

This new Lipid detergent may be used for crystallizing membrane proteins by using lipidic mesophases. This method has variously been referred to as the lipidic cubic phase or in meso method. The method has been shown to be quite versatile in that it has been used to solve X-ray crystallographic structures of prokaryotic and eukaryotic proteins, proteins that are monomeric, homo- and hetero-multimeric, chromophore-containing and chromophore-free, and alpha-helical and beta-barrel proteins.

Packaging

5 mL PTFE Vial with Screw Cap (850536O-25mg)

5 mL PTFE Vial with Screw Cap (850536O-1g)