Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Lectin from Arachis hypogaea (peanut) has been used: in enzyme-linked micro plate assay to detect β-D-galactose-N-acetylglucosamine in Immunohistochemical double stainingImmunohistochemical double staining for the detection of germinal centersin enzyme-linked microplate assayto detect β-D-galactose-N-acetylglucosamine

Biochem/physiol Actions

PNA does not agglutinate normal human erythrocytes, but strongly agglutinates neuraminidase treated erythrocytes. PNA has potent anti-T activity similar to the anti-T antibody in human sera. The lectin can be used to distinguish between human lymphocyte subsets.

Lectin from Arachis hypogaea (peanut) functions as an antigenic determinant for Thomsen-Friedenreich antigen (TF) and as mitogen for colorectal cancer stimulation cell division in normal colonic epithelium. It is therefore used as tumor marker.

General description

Peanut lectin (PNA) is a lectin or an agglutinin from the legume, Arachis hypogaea, found in peripheral venous blood in humans after ingestion of peanuts. PNA lectin is specific to the galactosyl (β-1,3) N-acetylgalactosamine.

Packaging

1, 5 mg in serum bottle

Package size based on protein content.

Physical form

Contains sodium citrate