Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

For research use only. Not for use in diagnostic procedures.Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Macrophage-derived chemokine (MDC) signals through the C-C chemokine receptor type 4 (CCR4). It chemo-attracts monocytes, dendritic cells and natural killer (NK) cells and aids in their function. The protein exerts human immunodeficiency virus (HIV) suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity but retains HIV suppressive activity. It is expressed in various cancers and is involved in recruitment of regulatory T cells (Treg) within a tumor.

General description

Human MDC / CCL22 enzyme-linked immunosorbent assay (ELISA) kit is an in vitro assay for the quantitative measurement of macrophage-derived chemokine (MDC) protein in biological samples, such as serum, plasma, cell culture supernatants, urine, and/or cell and tissue lysates.

Immunogen

Recombinant Human MDC

Other Notes

A sample Certificate of Analysis is available for this product.Please type the word sample in the text box provided for lot number.