Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

(S)-(−)-Perillic acid (PA) can be used as a starting material for the preparation of:,· Aryl amides, 4-(prop-1-en-2-yl)-N-(3-(trifluoromethyl)phenyl)cyclohex-1-ene-1-carboxamide and N-(4-(4-amino-2-methylphenethyl)-3-methylphenyl)-4-(prop-1-en-2-yl)cyclohex-1-ene-1-carboxamide, as in vitro antiproliferative active agents.Machaeriols and cannabinoid-related compounds as antimalarial agents. Tricyclic-β-lactone by treating with 1-chloro-N,N-2-trimethylpropenylamine and dimethylketomalonate, followed by addition of 9-azajulolidine.

Biochem/physiol Actions

Interferes with activity of p21^ras and other small G proteins by inhibiting post-translational cysteine isoprenylation.

General description

(S)-(-)-Perillic acid is a perillyl derivative with potent antimicrobial and anticancer activity. It can be prepared via bio-oxidation of R-(+)-limonene.

Packaging

1 g in glass bottle