Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
Cytidine-5′-monophospho-N-acetylneuraminic acid sodium salt has been used: as a standard in high-performance anion-exchange chromatography with pulsed amperometric detection (HPAEC-PAD) for nucleotide sugar analysis in Joubert syndrome type 10 (JBTS10) patient cells and control skin fibroblasts, As a substrate for the enzymatic sialylation of G2 glycoforms, resialylation assay, in in-vitro sialyltransferase assay
Biochem/physiol Actions
Cytosine 5′-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac) is used as a substrate for Golgi sialyltransferases to form sialic acid and its conjugates.
Cytidine-5′-monophospho-N-acetylneuraminic acid (CMP-Sialic acid) is a substrate for sialyltransferases. It is used for the enzymatic sialylation of glycans.
General description
Cytosine 5′-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac) is a sugar-nucleotide produced by CMP-Neu5Ac synthetase from CTP and Neu5Ac.
Packaging
1, 5 mg in glass bottle
25 mg in poly bottle
Preparation Note
Enzymatically prepared by the method of Schauer, R., et al., Hoppe Seyler′s Z. Physiol. Chem., 353, 883 (1972).CMP-NAN is very acid-labile.
Ce produit répond aux critères suivants: