Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Adenosine, periodate oxidized has been used: as a methylarginine transferase inhibitor in the human embryonic kidney (HEK)-293 T cells as a methylase inhibitor in H4 neurogliomaas a broad inhibitor of S-adenosylmethionine (AdoMet)-dependent methyltransferases in mouse embryo fibroblast NIH3T3 cells

Biochem/physiol Actions

Adenosine, periodate oxidized (Adox) is a protein arginine methyltransferases (PRMTs) inhibitor. It also inhibits the enzyme S-adenosylhomocysteine hydrolase and induces apoptosis. Its inhibitory effect on histone methyltransferases prevents histone methylation. Adox also elicits intrinsic cytotoxic properties.

Packaging

25, 100 mg in poly bottle