Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Lysine Oxidase from Trichoderma viride has been used in the preparation of luminescent biochip preparation.

Biochem/physiol Actions

Lysine Oxidase from Trichoderma viride catalyzes the formation of α-keto- ε-aminocaproate by the oxidative deamination of L-lysine. It displays anti-tumor functionality in cancer leukaemic cells. It is a tumor suppressor for squamous cell, fibroblast, ovarian and gastric tumors. Lysine oxidase also plays key role in connective tissue structural integrity and embryo development.

General description

Lysine Oxidase from Trichoderma viride is a homodimeric flavoenzyme corresponding to molecular mass of 112 kDa. It is stable at 65°C and is highly specific for L-lysine substrate. It comprises FAD-binding, substrate binding and a helical domain with distinct active site funnel.

Packaging

25 units in serum bottle

Physical form

Contains phosphate buffer salts and stabilizer

Unit Definition

One unit will catalyze the formation of 1 µmole of 6-amino-2-oxohexanoic acid from L-lysine per min at 37°C at pH 8.0.