L-Buthionine - sulfoximine ,>=97% (TLC)

Code: b2515-500mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.

L-Buthionine-sulfoximine has been used:as a s...


en savoir plus

Votre prix
$187.05 500MG
$224.46 inc. VAT

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.

L-Buthionine-sulfoximine has been used:as a selective activator for the induction of ferroptosis in rat apoptotic cellsas an inhibitor of γ-glutamylcysteine synthetase to study its effects on the viability and effectiveness of microspore embryogenesis (ME) induction in triticale and barleyas a glutathione synthesis blocker to study its effects on auranofin (AFN)-mediated interleukin-1β expression in murine alveolar macrophages

Biochem/physiol Actions

Blocks cellular resistance to chemotherapy by inhibiting γ-glutamylcysteine synthetase, a key enzyme in glutathione biosynthesis. Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.

Packaging

1, 5 g in poly bottle

500 mg in poly bottle

assay≥97% (TLC)
biological sourcesynthetic (organic)
formpowder
Gene Informationhuman ... GCLC(2729), GCLM(2730)
InChI keyKJQFBVYMGADDTQ-CVSPRKDYSA-N
InChI1S/C8H18N2O3S/c1-2-3-5-14(10,13)6-4-7(9)8(11)12/h7,10H,2-6,9H2,1H3,(H,11,12)/t7-,14?/m0/s1
mp224-226 °C
Quality Level200
shipped inwet ice
SMILES stringCCCCS(=N)(=O)CC[C@H](N)C(O)=O
solubilitywater: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
storage temp.−20°C
Code
Description
Unité de vente
Prix annoncé
Qté
B2515-1G
Unité:1G
Prix annoncé: $343.65
Source:Prix annoncé
B2515-5G
Unité:5G
Prix annoncé: $1,103.45
Source:Prix annoncé
Cas Number83730-53-4
Ce produit répond aux critères suivants: