S-(4-Nitrobenzyl) -6 - thioinosine, >=98%, solide

Code: n2255-250mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Inhibitor of equilibrative nucleoside transporters (ENTs), particularly adenosine transporters, in central nervous system and vascular smooth muscle.<...


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£409.00 250MG
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Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Inhibitor of equilibrative nucleoside transporters (ENTs), particularly adenosine transporters, in central nervous system and vascular smooth muscle.

Potent adenosine uptake inhibitor

General description

S-(4-Nitrobenzyl)-6-thioinosine (NBTI) belongs to the family of S6-substituted 6-thiopurine nucleosides, which regulate nucleoside transport mechanisms in animals. It acts as a ligand of adenosine transporter. Binding sites for NBTI is located on brain capillaries. It functions as a covalent photoaffinity probe for nucleoside transport.

Packaging

25 mg in glass bottle

100, 250 mg in poly bottle

assay≥98%
colorwhite
formsolid
Gene Informationhuman ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140), SLC29A1(2030)
InChI keyDYCJFJRCWPVDHY-LSCFUAHRSA-N
InChI1S/C17H17N5O6S/c23-5-11-13(24)14(25)17(28-11)21-8-20-12-15(21)18-7-19-16(12)29-6-9-1-3-10(4-2-9)22(26)27/h1-4,7-8,11,13-14,17,23-25H,5-6H2/t11-,13-,14-,17-/m1/s1
mp187-190 °C (lit.)
Quality Level100
SMILES stringOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(SCc4ccc(cc4)[N+]([O-])=O)ncnc23
solubility0.1 M NaOH: slightly soluble, 0.1 M HCl: slightly soluble, DMSO: soluble, H2O: insoluble
storage temp.2-8°C
Code
Description
Unité de vente
Prix annoncé
Qté
N2255-25MG
S-(4-Nitrobenzyl) -6 - thioinosine, >=98%, solide

Unité:25MG
Prix annoncé: £70.50
Source:Prix annoncé
AJOUTER
Cas Number38048-32-7
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