Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
Chlorothiazide has been used as a reference standard in parallel artificial membrane permeability assay (PAMPA). It has also been used to test its effect on blocking pendrin activity.
One of the first in the thiazide class of diuretics. The effect is sparing of calcium and lithium, but increases the excretion of sodium.
Biochem/physiol Actions
Chlorothiazide (CTLD) shows structural resemblance with hydrochlorothiazide by having a sulfonamide group, but exhibits a long action duration. CTLD is an inhibitor of carbonic anhydrase and is more potent than hydrochlorothiazide.
General description
Chlorothiazide (CTLD) is a thiazide-like diureticsand has antihypertensive effects.
Packaging
50 g in glass bottle
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