Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
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Biochem/physiol Actions
Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations.
General description
Isoniazid is a type of drug possessing antimycobacterial activity.It is used in the treatment of tuberculosis.
Chemical structure: pyridine
Packaging
5, 50, 250 g in poly bottle
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