Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Adenosine 5′-triphosphate disodium salt hydrate has been used:as a component of transfection mix for the transformation of CRISPR/Cas9 plasmid in parasitesin inflammasome activation assays in bone marrow derived macrophagesfor the stimulation of macrophagesin nucleotide synthesis

Biochem/physiol Actions

P₂ purinergic agonist; increases activity of Ca²⁺-activated K⁺ channels; substrate for ATP-dependent enzyme systems

General description

Adenosine 5′-triphosphate (ATP) is essential for biological processes including neurotransmission, signal transduction, muscle contraction and cardiac function. ATP is the major energy potential for living systems. They are released from cells under stress and play a key role in immune response. ATP release from injured neurons and consequent breakdown leads to generation of adenosine. ATP may serve as a therapeutic option in anaesthesia and intensive care medicine for the management of pain. Elevated ATP levels are indicative of cell damage and inflammation.

Packaging

1, 5, 10 g in poly bottle