Rifampicin, > = 97 %(HPLC) ,POUDRE

Code: r3501-5g D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Rifampicin is used to treat Tuberculosis and Tuberculosis-related mycobacterial infections. It is widely used as an antipruritic agent in the autoimmune cholestat...


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Votre prix
£427.00 5G

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Rifampicin is used to treat Tuberculosis and Tuberculosis-related mycobacterial infections. It is widely used as an antipruritic agent in the autoimmune cholestatic liver disease, primary biliary cirrhosis (PBC). It has been shown to cause hepatitis.

Biochem/physiol Actions

Rifampicin inhibits the assembly of DNA and protein into mature virus particles. It inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase, which results in cell death.

Mode of Action: Inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase.

Inhibits the assembly of DNA and protein into mature virus particles.

General description

Chemical structure: macrolide

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Product is sensitive to light and moisture.Store under inert gas. Keep in a dry place

Packaging

250 mg in glass insert

1, 5, 25 g in glass bottle

antibiotic activity spectrumGram-positive bacteria, Gram-negative bacteria, mycobacteria, viruses
assay≥97% (HPLC)
colorfaintly orange to red-brown
formpowder
InChI keyJQXXHWHPUNPDRT-WLSIYKJHSA-N
InChI1S/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,44-20+/t21-,23+,24+,25+,29-,34-,35+,39+,43-/m0/s1
mode of actionprotein synthesis | interferes
pI 4.84
pKa 7.9 (4-piperazine nitrogen), 1.7 (4-hydroxyl group)
Quality Level200
SMILES stringCO[C@H]1C=CO[C@@]2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)C(C)=CC=C[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(C=NN5CCN(C)CC5)c(O)c4c3C2=O
solubilityH2O: 1.3 mg/mL (pH 4.3), chloroform: soluble 50 mg/mL, DMSO: 100 mg/mL, H2O: 2.5 mg/mL at 25 °C (pH 7.3)
storage temp.−20°C
Code
Description
Unité de vente
Prix annoncé
Qté
R3501-1G
Unité:1G
Prix annoncé: £126.00
Source:Prix annoncé
R3501-250MG
Unité:250MG
Prix annoncé: £45.60
Source:Prix annoncé
R3501-25G
Unité:25G
Prix annoncé: £1,810.00
Source:Prix annoncé
Cas Number13292-46-1
Ce produit répond aux critères suivants: