Chlorure de Naftifine,

Code: n1790-50mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative. It is used topically to treat superficial dermatomycoses such as tinea pedis...


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Votre prix
$321.90 50MG

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative. It is used topically to treat superficial dermatomycoses such as tinea pedis, tinea cruris, and tinea corporis.

Biochem/physiol Actions

Allylamine compound that has antifungal and antimycotic activities. Naftifine inhibits fungal squalene epoxidase and prevents ergosterol biosynthesis. Naftifine also has antibiotic activity against Gram-positive and Gram-negative bacteria and has demonstrated anti-inflammatory properties.

Naftifine is an allylamine compound that has antifungal and antimycotic activities. Naftifine inhibits fungal squalene epoxidase and prevents ergosterol biosynthesis. Naftifine also has antibiotic activity against Gram-positive and Gram-negative bacteria. It has demonstrated anti-inflammatory properties such as a reduction in superoxide production and a reduction in polymorphonuclear leukocyte chemotaxis/endothelial adhesion. Naftifine appears to interfere with sterol biosynthesis by inhibiting the squalene 2,3-epoxidase. This inhibition results in decreased amounts of ergosterol and an accumulation of squalene in the cells.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Light sensitive.

Packaging

50, 500 mg in poly bottle

antibiotic activity spectrumfungi, Gram-positive bacteria, Gram-negative bacteria, yeast
assay≥99%
formpowder
InChI keyOLUNPKFOFGZHRT-YGCVIUNWSA-N
InChI1S/C21H21N.ClH/c1-22(16-8-11-18-9-3-2-4-10-18)17-20-14-7-13-19-12-5-6-15-21(19)20;/h2-15H,16-17H2,1H3;1H/b11-8+;
mode of actioncell wall synthesis | interferes, enzyme | inhibits
Quality Level200
SMILES stringCl.CN(CC=Cc1ccccc1)Cc2cccc3ccccc23
solubilityethanol: soluble 50 mg/mL
storage temp.2-8°C
Code
Description
Unité de vente
Prix annoncé
Qté
N1790-500MG
Unité:500MG
Prix annoncé: $1,141.15
Source:Prix annoncé
Cas Number65473-14-5
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