Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
Folic acid has been used:to induce acute kidney injury in miceas a supplement to cultivate MCF-7 breast cancer cells.to construct folate or TNF-related apoptosis-including ligand (TRAIL)-conjugated nanomicelles
Biochem/physiol Actions
Folic acid (FA) and dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF), which in turn supports ‘;one carbon’; transfer. Tetrahydrofolates are required for de novo synthesis of purines, thymidylic acid and various amino acids and for post-translational methylation (epigenetics).
Enzyme cofactor essential for the synthesis, methylation, and repair of DNA. Folic acid supplements may reduce colorectal cancer risk.
Packaging
1, 10, 25, 100 g in glass bottle
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