Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
Kolliphor® EL has been used as a detergent to improve the solubility of dye and to increase the transmembrane permeation. It has been used as a vehicle for drug/stimulant delivery in cells.
Used to emulsify and solubilize oils and other water-insoluble substances. Cremophor is the brand name for a range of non-ionic polyethoxylated detergents. It was originally developed for use as solubilizers and emulsifiers.This research grade product is intended for use in R&D and development only.
Biochem/physiol Actions
Kolliphor® EL is used in lipid-based formulations for drugs and solubilization of cosmetics. Kolliphor EL is suitable for the production of semi-solid and liquid formulations of water-insoluble actives and other hydrophobic compounds. Due to its emulsification functionality, it finds application in biological membrane- based drug transport studies.
General description
Kolliphor® EL is polyethylene oxide surfactant and is viscous in nature. It has a hydrophobic-lipophilic balance value in the range of 12-14.
Kolliphor® EL is a nonionic solubilizer and emulsifier made by reacting castor oil with ethylene oxide. It is a pale yellow oily liquid that is clear at temperatures above 26°C. It has a faint but characteristic odour.
Legal Information
Kolliphor is a registered trademark of BASF
Cremophor is a registered trademark of BASF SE
Other Notes
A derivative of castor oil and ethylene oxide.
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