Sel de sulfate de colistine, > = 15 000 u/mg

Code: c4461-1g D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Analysis Note

Freely soluble in water, practically insoluble in acetone and in ethanol (96%)

Application

Colistin sulfate is used to permeabilize...


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Votre prix
£225.00 1G
DEMANDER

Non disponible en dehors du Royaume-Uni et de l'Irlande

Analysis Note

Freely soluble in water, practically insoluble in acetone and in ethanol (96%)

Application

Colistin sulfate is used to permeabilize bacterial cell membranes and to study mannose-resistant haemagglutination and antibiotic resistance in certain organisms such as A. baumannii . It has been used to study hephrotoxicity in the rat kidney , and MICs, time-kill kinetics, and postantibiotic effect (PAE) against Pseudomonas aeruginosa .

Biochem/physiol Actions

Mode of Action: Binds to lipids on the cell cytoplasmic membrane of Gram-negative bacteria and disrupts the cell wall integrity.Antimicrobial spectrum: Gram-negative bacteria.

Mode of Action: Binds to lipids on the cell cytoplasmic membrane of Gram-negative bacteria and disrupts the cell wall integrity. Antimicrobial spectrum: Gram-negative bacteria. It is proposed that renal reabsorption of colistin may involve organic cation transporters and peptide transporters and that the process is sensitive to pH .

General description

Chemical structure: peptide

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Packaging

100 mg in poly bottle

1 g in poly bottle

antibiotic activity spectrumGram-negative bacteria
formpowder
InChI keyZJIWRHLZXQPFAD-LRYSGCCDSA-N
InChI1S/C53H100N16O13.H2O4S/c1-9-30(6)12-10-11-13-41(72)60-33(14-20-54)48(77)69-43(32(8)71)53(82)65-36(17-23-57)45(74)64-38-19-25-59-52(81)42(31(7)70)68-49(78)37(18-24-58)62-44(73)34(15-21-55)63-50(79)39(26-28(2)3)67-51(80)40(27-29(4)5)66-46(75)35(16-22-56)61-47(38)76;1-5(2,3)4/h28-40,42-43,70-71H,9-27,54-58H2,1-8H3,(H,59,81)(H,60,72)(H,61,76)(H,62,73)(H,63,79)(H,64,74)(H,65,82)(H,66,75)(H,67,80)(H,68,78)(H,69,77);(H2,1,2,3,4)/t30?,31-,32-,33+,34+,35+,36+,37+,38+,39+,40-,42+,43+;/m1./s1
mode of actioncell membrane | interferes
Quality Level200
specific activity≥19,000 IU/mg
storage temp.2-8°C
Code
Description
Unité de vente
Prix annoncé
Qté
C4461-100MG
Sel de sulfate de colistine, > = 15 000 u/mg

Unité:100MG
Prix annoncé: £51.80
Source:Prix annoncé
AJOUTER
Cas Number1264-72-8
Hazard Class6.1
Un Number2811
Pack GroupIII
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