Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
Pinacidil monohydrate has been used:in repolarization studies by infusing into left anterior descending artery (LAD)to induce ATP-sensitive K+ (KATP) current in ventricular myocytes for electrophysiological studiesas a KATP opener to treat myocardial cells
Biochem/physiol Actions
Pinacidil is a KATP channel agonist. It protects cardiomyocytes by preventing loss of mitochondrial membrane potential. It prevents the caspase 3 activation in hypoxia/reoxygenation injury.
K+ channel activator; antihypertensive.
Packaging
100, 500 mg in poly bottle
1 g in poly bottle
Ce produit répond aux critères suivants: