Ganaxolone, (le produit est pur à partir d'une analyse élémentaire, NMR, MS, rotation optique ET point de fusion), (HPLC), solide

Code: g7795-5mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Ganaxolone (3alpha-hydroxy-3beta-methyl-5alpha-pregnane-20-one) is a positive allosteric modulator of the GABAA receptor subtype; synthetic analog of ...


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Votre prix
£136.00 5MG
£163.20 inc. VAT
DEMANDER

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Ganaxolone (3alpha-hydroxy-3beta-methyl-5alpha-pregnane-20-one) is a positive allosteric modulator of the GABAA receptor subtype; synthetic analog of the endogenous neurosteroid allopregnanolone; effective against chemically induced seizures in rats and mice. Ganaxolone is an orally active analog of allopregnanolone that is not converted to the hormonally active 3-keto form. The enhanced anticonvulsant potency of ganaxolone after neurosteroid withdrawal supports the use of ganaxolone as a specific treatment for perimenstrual catamenial epilepsy.

Features and Benefits

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

5, 25 mg in glass bottle

Quality

The product is pure based on elemental analysis, NMR, MS, optical rotation and melting point.

assay≥98% (HPLC)
colorwhite
formsolid
Gene Informationhuman ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879)mouse ... Gabrg2(14406)
InChI keyPGTVWKLGGCQMBR-FLBATMFCSA-N
InChI1S/C22H36O2/c1-14(23)17-7-8-18-16-6-5-15-13-20(2,24)11-12-21(15,3)19(16)9-10-22(17,18)4/h15-19,24H,5-13H2,1-4H3/t15-,16-,17+,18-,19-,20+,21-,22+/m0/s1
Quality Level100
SMILES string[H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@H](C(C)=O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CC[C@@](C)(O)C2
solubilityDMSO: ≥2 mg/mL, H2O: insoluble
storage temp.2-8°C
Code
Description
Unité de vente
Prix annoncé
Qté
G7795-25MG
Ganaxolone, (le produit est pur à partir d'une analyse élémentaire, NMR, MS, rotation optique ET point de fusion), (HPLC), solide

Unité:25MG
Prix annoncé: £546.00
Source:Prix annoncé
AJOUTER
Cas Number38398-32-2
Ce produit répond aux critères suivants: