Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Diazoxide has been used for diazoxide infusion. It has also been used to prevent depolarization for K⁺-induced exocytosis.

Biochem/physiol Actions

Selective ATP-sensitive K⁺ channel activator in both vascular smooth muscle and pancreatic β-cells; antihypertensive.

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Schering Plough. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

General description

Diazoxide is a nondiuretic benzothiadiazine, which is used for the treatment of hypoglycemia,von Gierke′s disease, acute and malignant hypertension. It acts as a beta cell K_ATP channel opener. Diazoxide prevents the secretion of insulin.