Sel de sodium acide Oleoyl - l - alpha-lysophosphatidique, >=98%, solide

Code: l7260-5mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Oleoyl-L-α-lysophosphatidic acid sodium salt has been used:for the activation of Ras homolog gene family, member A (RhoA) and expression of claudin-1 in human bre...


en savoir plus

Votre prix
£212.00 5MG

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Oleoyl-L-α-lysophosphatidic acid sodium salt has been used:for the activation of Ras homolog gene family, member A (RhoA) and expression of claudin-1 in human breast cancer epithelial cell linein RH7777 cells for cyclic adenosine monophosphate (cAMP) accumulation assay and calcium mobilisation assayin vitro luciferase assay and live-cell imaging

Biochem/physiol Actions

Endogenous agonist for LPA1 and LPA2 receptors. LPA does not induce angiogenesis, but has effects on endothelial cell physiology that are similar to those of sphingosine 1-phosphate. Induces cell migration of cancer and non-cancer cells.

Caution

Hygroscopic, photosensitive

Features and Benefits

This compound is featured on the Lysophospholipid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

General description

Lysophosphatidic acid (LPA) is an essential metabolite for membrane biosynthesis. LPA interacts with the G protein-coupled receptors (GPCRs), called the LPA receptor and mediates signaling. Oleoyl-L-α-lysophosphatidic acid activates the receptor LPA4. In keratinocytes, oleoyl-L-α-lysophosphatidic acid promotes growth to some extent.

Packaging

1, 5, 25 mg in glass bottle

Preparation Note

Prepared by the action of phospholipase A on L-α-phosphatidic acid, dioleoyl.

assay≥98%
colorwhite
formsolid
InChI keyCHJOEWDRTPWOCY-TTWKNDKESA-N
InChI1S/C21H41O7P.Na.H/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26;;/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26);;/b10-9+;;
Quality Level200
SMILES stringO[C@](COP([O-])(O)=O)([H])COC(CCCCCCC/C=CCCCCCCCC)=O.[Na+]
storage temp.−20°C
Code
Description
Unité de vente
Prix annoncé
Qté
L7260-1MG
Unité:1MG
Prix annoncé: £57.20
Source:Prix annoncé
L7260-25MG
Unité:25MG
Prix annoncé: £849.00
Source:Prix annoncé
Cas Number22556-62-3
Ce produit répond aux critères suivants: