Z-Ile-Glu (O - ME)- Thr - Asp(O - Me) fluorométhyle cétone, >=90% (TLC), poudre

Code: c1230-1mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Amino Acid Sequence

Z-Ile-Glu-OMe-Thr-Asp-OMe-FMK

Application

Z-Ile-Glu(O-ME)-Thr-Asp(O-Me) fluoromethyl ketone (Z-IETD-FMK) has been used as a c...


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Votre prix
£441.00 1MG
DEMANDER

Non disponible en dehors du Royaume-Uni et de l'Irlande

Amino Acid Sequence

Z-Ile-Glu-OMe-Thr-Asp-OMe-FMK

Application

Z-Ile-Glu(O-ME)-Thr-Asp(O-Me) fluoromethyl ketone (Z-IETD-FMK) has been used as a caspase-8 inhibitor:to study the activity of caspase-8 in porcine kidney cellsto study its effects on porcine parvovirus (PPV)-induced caspase-3 activity in steroidogenic luteal cellsto study its effects on retinal ganglion and astroglia in rat eyes

Biochem/physiol Actions

Z-Ile-Glu(O-ME)-Thr-Asp(O-Me) fluoromethyl ketone (Z-IETD-FMK) is an irreversible and cell-permeable caspase-8 inhibitor.

Features and Benefits

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

assay≥90% (TLC)
biological sourcesynthetic (organic)
formpowder
InChI keyCTXDBLYOEUERAT-VUVYEONESA-N
InChI1S/C28H39FN4O11/c1-4-15(2)23(33-28(43)44-14-17-8-6-5-7-9-17)26(41)30-18(10-11-21(36)37)25(40)32-24(16(3)34)27(42)31-19(12-22(38)39)20(35)13-29/h5-9,15-16,18-19,23-24,34H,4,10-14H2,1-3H3,(H,30,41)(H,31,42)(H,32,40)(H,33,43)(H,36,37)(H,38,39)/t15-,16+,18-,19-,23-,24-/m0/s1
Quality Level200
shipped indry ice
SMILES stringCC[C@H](C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)O)C(=O)N[C@@H](CC(O)=O)C(=O)CF
solubilityDMSO: 20 mM, clear, colorless to light yellow, methanol: 10 mg/mL
storage temp.−20°C
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