Bisindolylmaleimide IV, > = 98% (TLC) , solide

Code: b3306-1mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Bisindolylmaleimides (BIM) comprises a group of 11 compounds from BIM-I to BIM-XI. BIMs act as an inhibitor of protein kinase C (PKC). They are derive...


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$147.25 1MG
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Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Bisindolylmaleimides (BIM) comprises a group of 11 compounds from BIM-I to BIM-XI. BIMs act as an inhibitor of protein kinase C (PKC). They are derived from staurosporine. BIM IX due to its proapoptotic functionality could be useful in targeting tumor proliferation.

assay≥98% (TLC)
biological sourcesynthetic (organic)
colordark red
formsolid
Gene Informationhuman ... CDK2(1017), EGFR(1956)rat ... Prkca(24680)
InChI keyDQYBRTASHMYDJG-UHFFFAOYSA-N
InChI1S/C20H13N3O2/c24-19-17(13-9-21-15-7-3-1-5-11(13)15)18(20(25)23-19)14-10-22-16-8-4-2-6-12(14)16/h1-10,21-22H,(H,23,24,25)
Quality Level200
SMILES stringO=C1NC(=O)C(c2c[nH]c3ccccc23)=C1c4c[nH]c5ccccc45
solubilitymethanol: soluble, DMSO: soluble
storage temp.−20°C
Cas Number119139-23-0
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