Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

IgG, IgA, IgM, Factor H, Factor B, or albumin: ≤trace amounts

General description

Native factor D from human serum. Single-chain glycoprotein composed of 222 amino acids, present in normal human serum at about 1.4 µg/ml. Serine protease that cleaves, and thus activates, Factor B during activation of complement via the alternative pathway. Has recently been shown to be identical to adipsin, a serine protease secreted into the bloodstream by adipocytes.

Native factor D from human serum. Single-chain glycoprotein composed of 222 amino acids present in normal human serum at about 1.4 µg/ml. Serine protease that cleaves, and thus activates, Factor B during activation of complement via the alternative pathway. Has recently been shown to be identical to adipsin, a serine protease secreted into the bloodstream by adipocytes.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Jing, H., et al. 1999. EMBO J.18, 804.Volankis, J.E., et al. 1985. N. Engl. J. Med. 312, 395.Niemann, M.A., et al. 1984. J. Immunol. 132, 809.

Packaging

25 µg in Plastic ampoule

Physical form

In PBS, pH 7.2.

Preparation Note

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Warning

Toxicity: Standard Handling (A)