Non disponible en dehors du Royaume-Uni et de l'Irlande

General description

Native apolipoprotein E from human plasma. A component of VLDL and a subclass of HDL. Serves as a ligand for LDL receptors, where it participates in the transport and redistribution of cholesterol and other lipids. Also functions in immunoregulation, cell growth, and differentiation. Present in normal plasma at concentrations of 50 µg/ml.

Native apolipoprotein E from human plasma. A component of VLDL and of a subclass of HDL. Present in normal plasma at concentrations of 50 µg/ml. Serves as a ligand for LDL receptors, where it participates in the transport and redistribution of cholesterol and other lipids. Also functions in immunoregulation and cell growth differentiation. Inhibits mitogen-induced T-lymphocyte proliferation and modulation of smooth muscle cell differentiation.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Kelly, M.E., et al. 1994. Cell Immunol. 159, 124.Mahley, R.W. 1988. Science 240, 622.Rall, S.C., et al. 1986. Methods Enzymol. 128, 273.

Packaging

50 µg in Plastic ampoule

Please refer to vial label for lot-specific concentration.

Physical form

In 50 mM NH₄HCO₃, pH 8.0.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Warning

Toxicity: Standard Handling (A)