44583-1mg Display Image

Hydrochlorure de doxorubicine, (HPLC), adapté à la fluorescence, 98,0- 102,0% (HPLC)

Code: 44583-1mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Doxorubicin was used to induce apoptosis, and to induce cardiotoxicity in SK-N-MC cells . It is used to inhibit macromolecular biosynthesis.

Biochem...


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Votre prix
$70.04 1MG
$84.05 inc. VAT
DEMANDER

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Doxorubicin was used to induce apoptosis, and to induce cardiotoxicity in SK-N-MC cells . It is used to inhibit macromolecular biosynthesis.

Biochem/physiol Actions

Doxorubicin ia an antitumor antibiotic that intercalates DNA and inhibits macromolecular biosynthesis. DNA replication is haulted due to the inhibition of topoisomerase II. It is an inhibitor of reverse transcriptase and RNA polymerase and is an immunosuppressive agent .

General description

Chemical structure: tetracycline

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Packaging

1, 10, 50 mg in glass bottle

Bottomless glass bottle. Contents are inside inserted fused cone.

antibiotic activity spectrumneoplastics
assay98.0-102.0% (HPLC)
biological sourcesynthetic
colororange to dark red
fluorescenceλex 470 nm; λem 585 nm in ethanol
formsolid
Gene Informationhuman ... TOP2A(7153)
InChI keyMWWSFMDVAYGXBV-RUELKSSGSA-N
InChI1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1
mode of actionenzyme | inhibits, DNA synthesis | interferes
mp216 °C (dec.) (lit.)
Quality Level200
SMILES stringCl[H].COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO
solubilityH2O: 50 mg/mL, clear, orange to red, THF: soluble, methanol: soluble, ethanol: soluble, DMSO: soluble
storage temp.2-8°C
suitabilitysuitable for fluorescence
Code
Description
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Qté
44583-10MG
Hydrochlorure de doxorubicine, (HPLC), adapté à la fluorescence, 98,0- 102,0% (HPLC)

Unité:10MG
Prix annoncé: $350.90
Source:Prix annoncé
AJOUTER
44583-50MG
Hydrochlorure de doxorubicine, (HPLC), adapté à la fluorescence, 98,0- 102,0% (HPLC)

Unité:50MG
Prix annoncé: $1,300.65
Source:Prix annoncé
AJOUTER
Cas Number25316-40-9
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