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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Norfloxacin may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations, biological fluids and sewage using various chromatography techniques.

Biochem/physiol Actions

Norfloxacin blocks DNA replication by interfering with an ATP-induced structural transition of DNA complexed with DNA gyrase (topoisomerase).Mode of action: inhibits bacterial DNA replicationAntimicrobial spectrum: Gram-negative bacteria; less effective against Gram-positive bacteria

General description

Norfloxacin is an antimicrobial drug, belonging to the class of fluoroquinolones (FQs), which shows broad-spectrum activity against a wide range of Gram-negative and Gram-positive organisms.

Legal Information

VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH