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Analysis Note

The target analytes include polar compounds, non-polar compounds, and structural isomers.

Footnote

Care & Use Guide for Supel^™ Carbon LC, 2.7 µm HPLC ColumnInstalling Supel^™ Carbon LC Guard Cartridges

General description

Supel^™ Carbon LC is a high-speed, ultra-high performance liquid chromatography column based on 200 Å porous graphitic carbon (PGC) particle technology. The PGC particle provides a 100% carbon plane for the analytes to interact with via hydrophobic interactions and through ionic interactions via the polar retention effect on graphite (PREG) effect. This particle design exhibits high column efficiency for polar compoundsand enhanced retention of compounds typically requiring hydrophilic interaction liquid chromatography (HILIC) to retain. Through the use of patent-pending synthetic procedures, a narrow particle size distribution is prevalent with this technology, further enhancing the chromatographic performance that this column can display.

Legal Information

Supel is a trademark of Sigma-Aldrich Co. LLC

Recommended products

The use of a Supel^™ Carbon LC 2.7 µm guard cartridge is recommended for the protection of your HPLC column. Guard cartridge kit, Cat. No. 59996-U, includes the appropriate Supel^™ Carbon LC, 2.7 µm HPLC guard cartridge as well as the necessary holder. A pack of three replacement guard cartridges may be purchased using Cat. No. 59995-U. Additionally, a stand-alone guard cartridge holder may be purchased using Cat. No. 59999-U.