Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Aurora^®-DSG (Distearoylglycerol) nanoparticles aid in improving contrast in liposome and membrane preparations in cryo-transmission microscopy imaging. They are useful in lipid research as they provide good resolution image of the lipid bilayer on incorporation. Their biophysical interaction with lipid bilayers is exploited in many membrane research studies. Confocal, atomic force and high-resolution microscopy utilize the incorporation of Aurora^® into the heterogeneous bilayers, as they do not hamper the lipid layer properties and composition.

General description

This new conjugate from Avanti consists of an Aurora^® gold cluster capped with triphenylphosphine ligands and a single diglyceride ligand. Fifty-five gold atom nanoparticles, first described by Schmid, are fascinating structures that are commonly used for contrast agents in various imaging applications. Ideally this particle, unlike larger colloidal style particles, is less intrusive to the target application and behaves like an organic entity instead of a foreign metallic probe. They also are a great generic platform for bottom up synthesis of novel, gold-centered nanostructures due to the ease and completeness of ligand exchange reactions. This complex is readily visible under TEM and can also be viewed in optical microscopes if further processed using a silver development procedure.

Legal Information

Aurora is a registered trademark of Avanti Polar Lipids, Inc.

Packaging

5 mL PTFE Vial with Screw Cap (550001P-500ug)