c-Myc mRNAs have been designed to produce high expression level of c-Myc protein. OZB mRNAs are produced by in vitro transcription. mRNAs are stabilized at the 5’ end by modified nucleotides capping (Cap1) and contain a poly(A) tail at the 3’ end. Sequences have been optimized to yield improved stability and performance. C-Myc mRNA #MRNA58 does not bear any additional nucleotide modifications while #MRNA59 is modified with 5-methoxyuridine (5moU), #MRNA60 is modified with N1-methyl-pseudouridine to reduce innate immune response.
- Length : 1584 nt .
- Molecular weights: MRNA58: 512800 g/mol g/mol; MRNA59: 518800 g/mol; MRNA60: 515800 g/mol.
This product has met the following criteria: