Not available outside of the UK & Ireland.

Amino Acid Sequence

Val-Ile-Leu-Ser-Leu-Asp-Val-Pro-Ile-Gly-Leu-Leu-Arg-Ile-Leu-Leu-Glu-Gln-Ala-Arg-Tyr-Lys-Ala-Ala-Arg-Asn-Gln-Ala-Ala-Thr-Asn-Ala-Gln-Ile-Leu-Ala-His-Val-NH2

Application

Mouse urocortin II can be used for immunohistochemistry.

Biochem/physiol Actions

Urocortin II is a CRF-related neuropeptide having high affinity for CRF2 receptor. It stimulates protein kinase A through CRF2 receptor and increases the contractility in rabbit ventricular myocytes. It also facilitates pro-inflammatory effects in human intestinal cells through corticotropin-releasing hormone receptor 2α.

corticotropin-releasing factor (CRF) peptide

Other Notes

Lyophilized from 0.1% TFA in H2O

Packaging

500 µg in glass bottle