Fibroblast growth factor 8a (FGF-8a) is a member of the FGF family and plays a key role in the regulation of embryogenesis, cellular proliferation, differentiation, and migration. FGF-8a is often used for the differentiation of induced pluripotent stem cells, embryonic stem cells, and neural stem cells.

FGF-8a is a spliced form of FGF-8, a heparin-binding protein that targets mammary and non-mammary cells expressing the FGF receptors. A 21.3 kDa highly pure, bioactive recombinant protein produced in an animal-free expression system. This protein is animal-origin free (AOF), carrier protein-free, tag-free, and non-glycosylated to ensure a pure homogenous protein with exceptional lot-to-lot consistency. Qk059 is suitable for enhanced reproducibility and physiologically relevant cultures.

• High purity human FGF-8a protein (Uniprot: P55075-2)
• >98%, by SDS-PAGE quantitative densitometry
• 21.3 kDa
• Expressed in E. coli
• Animal-origin free (AOF) and carrier protein-free
• Manufactured in our Cambridge, UK laboratories
• Lyophilised from HEPES/NaCl/mannitol
• Resuspend in water at >100µg/mL, prepare single use aliquots, add carrier protein if desired and store frozen at -20°C or -80°C