Human BMP-4 (bone morphogenetic protein 4) is a key regulator of embryogenesis and supports the differentiation of embryonic stem cells and induced pluripotent stem cells. In addition, BMP-4 protein plays roles in the differentiation of mesenchymal cells to adipocytes, epithelial cancer EMT, and regulating neuronal and glial cell development.

Qkine BMP-4 is a highly pure, animal origin-free and carrier protein-free 24 kDa disulphide–linked bioactive dimer comprised of the mature domain of human BMP-4 protein.

• High purity optimised human BMP-4 protein (Uniprot: P12644)
• >98%, by SDS-PAGE quantitative densitometry
• 24 kDa (dimer)
• Expressed in E. coli
• Animal origin-free (AOF) and carrier protein-free
• Manufactured in our Cambridge, UK laboratories
• Lyophilised from acetonitrile, TFA
• Resuspend in 10mM HCl at >100µg/mL (provided with protein and free of charge), prepare single use aliquots, add carrier protein if desired and store frozen at -20°C or -80°C